Drug-interaction-induced rhabdomyolysis

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Drug-induced rhabdomyolysis.

PURPOSE OF REVIEW Drug-induced rhabdomyolysis is a common syndrome that is complex and potentially life threatening. This article reviews the pathophysiology, clinical presentations, and common compounds that cause drug-induced rhabdomyolysis. RECENT FINDINGS The list of drugs and inciting agents that cause rhabdomyolysis is quite extensive. Rhabdomyolysis is defined as skeletal muscle injury...

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Diclofenac- and Pantoprazole-Induced Rhabdomyolysis: A Potential Drug Interaction

BACKGROUND Drugs represent one of the etiologic causes of acute rhabdomyolysis (AR) with drug-induced rhabdomyolysis most commonly associated with HMG-CoA reductase inhibitors. AR etiology can also result from the use of diclofenac, a non-steroidal anti-inflammatory drug, and omeprazole, a proton pump inhibitor. Cases of AR triggered by pantoprazole have never before been reported, although it ...

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ADVERSE DRUG REACTION Colchicine induced rhabdomyolysis

A case of colchicine induced rhabdomyolysis is reported. A 73 year old man with ischaemic heart disease, atrial fibrillation, chronic congestive cardiac failure, and chronic gout presented with diVuse muscle pain. He had been taking an increased dose of colchicine (1.5 mg daily) for an exacerbation of gout for six weeks before the presentation. Investigations confirmed the diagnosis of rhabdomy...

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Drug-induced rhabdomyolysis--mechanisms and management.

Since the original reports of patients with myoglo-bin-induced renal failure following crush injury during World War II,1 the aetiology of acute rhabdomyolysis has diversified. The causes include polymyositis, heat stroke, prolonged convulsions, marathon running, hypokalaemia and viral illness (Epstein-Barr, influenza and coxsackie viruses). Of late, drugs, including alcohol, have assumed great...

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Rhabdomyolysis secondary to drug interaction between atorvastatin, omeprazole, and dexamethasone

Concomitant administration of atorvastatin, omeprazole, and dexamethasone has been shown to increase the serum concentration of serum hydroxymethylglutaryl coenzyme A which can be associated with elevation of creatine kinase and an increased risk of severe myopathy and rhabdomyolysis. In this paper, we report a case of a 60-year-old female patient with stage IV colon cancer and compromised hepa...

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ژورنال

عنوان ژورنال: Nephrology Dialysis Transplantation

سال: 1996

ISSN: 1460-2385,0931-0509

DOI: 10.1093/ndt/11.9.1846